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Stem Cell Therapy for Ankle Sprains and Injuries

Stem Cells for Sports InjuriesAnkle sprain is a common injury caused by the stretch or tear of ligament. Ligaments, fibrous tissues that serve as connections between bones, are important structures for joint stability. Sprained ankles are reported in greater than 23,000 people each day in the US.

Depending on the severity, ankle sprains are classified as Grade I, II or III. Grade I sprain involves slight stretching of the ligaments, and can be overcome with stretching exercises. Grade II, on the other hand, involve partially torn ligaments, and requires splint or cast for healing.
Stem Cell Therapy for Sports Injuries
Finally, Grade III sprains are characterized by the complete tear of ligaments, and surgery is necessary in these case. Grades II and III sprains may involve the severing of blood vessels with the presence of black / blue discoloration at the site.

Causes: An ankle sprain is caused by the abnormal or excessive stress on the ligaments holding the ankle bones together. Typical causes of ankle sprains are sports-related, or accidental twisting of the ankle joint.

Three bones make up the ankle joint in humans—the tibia, fibula and talus. Most commonly, ankle sprains involve injury to the talofibular ligament, which is located in the front and outer part of the ankle joint.


An X-ray or MRI can identify the type of ankle sprain. Self-care measure for ankle sprains include rest, elevation of the foot, cold application to the area and pain medications (e.g. ibuprofen or naproxen).

Although most ankle sprains get better without further complications, some cases may require surgery. For these types of difficult sprains, stem cell therapy may be considered along with surgery to enhance the speed and quality of recovery.

Innovative Therapies

By using the body’s own adult stem cells, doctors can now promote repair and regeneration at the sites of injury and damage. The process involves the extraction of stem cells from the bone marrow, usually at the back hip iliac bone area, with the help of a needle.

This is an outpatient procedure undergone through X-ray or ultrasound guidance. The process is not painful and is generally well-tolerated. The extracted bone marrow is then concentrated in the laboratory to enrich for stem cells.

During this time, the patient’s blood sample may also be taken to concentrate for platelets—platelet-rich plasma (PRP). The stem cell preparation alStem Cells for Spinal Discong with the PRP solution is later injected into the injury site to start the natural healing process. PRP preparations are known to generate growth factors that facilitate the stem cell growth and differentiation. During the injection step, advanced imaging systems, such as fluoroscopy and ultrasound, is done to precisely deliver the stem cells to the right location.

Options for ankle stem cell injections may include:

  • Bone Marrow Derived Stem Cell Therapy
  • Amniotic Derived Stem Cell Therapy
  • Adipose Derived Stem Cell Therapy
  • Platelet Rich Plasma Therapy

Advantages of stem cell therapy include:

  • superior recovery using the body’s own stem cell reserves
  • avoidance of side effects from the continued usage of pain medications
  • good tolerance to the stem cells
  • anti-inflammatory effect of stem cells to control pain and swelling naturally.

Please contact us at R3 Stem Cell Clinics to get an evaluation whether you are eligible for stem cell therapy for your ankle injury. Get back on the field faster, avoid surgery!


  2. Soomekh DJ. Current concepts for the use of platelet-rich plasma in the foot and ankle. Clin Podiatr Med Surg. 2011;28(1):155-170.
  3. Giannini S, Buda R, Cavallo M, et al. Cartilage repair evolution in post-traumatic osteochondral lesions of the talus: from open field autologous chondrocyte to bone-marrow-derived cells transplantation. Injury. 2010;41(11):1196-1203.

Amniotic and Umbilical Cord Stem Cell Treatments

The most revolutionary regenerative medicine treatments now being offered include amniotic and umbilical stem cell treatments. These are FDA regulated and contain growth factors, hyaluronic acid, cytokines and stem cells.

Stem Cell Therapy Offers
Nonoperative Options

With a third of the US suffering from chronic pain, and over a milion each year
undergoing joint replacements in the US, stem cell therapy has a large target audience.
Whether you have a stem cell procedure to get back into sports, avoid hip or knee
replacement or avoid back surgery, regenerative medicine can help!

Contact Us Now!

Corporate Address: R3 Stem Cell
R3 Stem Cell, LLC
32531 N Scottsdale
Ste 105-559
Scottsdale AZ 85266

Phone: (844) GET-STEM
Fax: (888) 892-1831

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