Lyme disease is an infectious disease transmitted through tick bites. The deer tick is the most common one to harbor the Borrelia burgdorferi organism that is associated with Lyme disease. When untreated, Lyme disease develops into an autoimmune disorder. In the U.S., 96% of cases are from the Northeastern and Mid-Western regions. Lyme disease affects around 300,000 persons each year in America.
Most long-term effects of Lyme disease are not curable at this time. The primary focus of stem cell therapy is to stimulate the growth of healthy cells and tissues to replace those lost or damaged by the condition. Researchers are currently improving technologies and enhancing the therapies involving stem cells. With stem cell therapy, the cells are harvested from the patient’s own bone marrow, fat tissue, or spinal fluid.
Studies where Stem Cells are used in Lyme Disease
The latest stem cell research for Lyme disease is occurring at the Genome Institute of Singapore, which involves identifying and investigating genetic stem cell factors. These studies provide important clues as to how stem cells work. Adult stem cells work as building blocks to replenish dying cells and regenerate damaged structures. In 2008, a research team from Albany Medical College used stem cells for Lyme disease, with the goal of reducing duration of arthritis associated with the chronic condition. Their findings used mouse subjects with Lyme disease, and they found that the immune response properties were important in the stem cell therapy.
A study found that that stem cells activated T-cells in mice subjects, and this proved they could kill or clear Lyme disease bacteria in animal models. Researchers are adding to a body of evidence that show stem cells work for preventing disease progression. Mice who did not have the T-cells were not as able to clear the bacteria out of their bodies, and they went on to develop chronic arthritis. The stem cell mice did not. Stem cells
A recent case study involved the use of human embryonic stem cells in two patients. One patient had multiple sclerosis and the other had Lyme disease. The embryonic stem cells were given to the 30-year-old woman with Lyme disease, as well as the 42-year-old man with MS. Following treatment, both people had improved neurological function regarding cognition, muscle strength, stamina, and coordination. Imaging studies also showed brain scan improvements in these patients. Use of stem cells continue to support scientists’ theory that stem cells are beneficial for treating neurological conditions.
Benefits of Stem Cell Therapy for Lyme Disease
Regardless of ethical concerns, human embryonic stem cells are being used to treat Lyme disease in clinical trials. These cells can transform into many different tissue types and structures. There are many benefits for use of stem cells to treat Lyme disease. They have the ability to regenerate damaged nerve tissue, stop or reverse neurological damage, and eliminate the bacteria from the body.
Clinical trials involve culturing neural stem cells in the laboratory and then transplanting them into the brain or spinal cord of patients to slow or reverse disease progression. The long-term damage from a Lyme disease infection can be improved by use of embryonic stem cells, as well as adult stem cells derived from adipose tissue or bone marrow.
Shroff, G. (2016). Transplantation of human embryonic stem cells in patients with multiple sclerosis and Lyme disease. American Journal of Case Reports, 17, 944-949.
FIND A DOCTOR
R3 Stem Cell offers stem cell therapy for Lyme Disease using non-embryonic stem cells at Centers of Excellence. If you or a loved one would like to consider regenerative therapy for Lyme Disease, please call us at (844) GET-STEM or contact us HERE.
The most revolutionary regenerative medicine treatments now being offered include amniotic and umbilical stem cell treatments. These are FDA regulated and contain growth factors, hyaluronic acid, cytokines and stem cells.