Call US NOW (844) GET-STEM

Call US NOW (844) GET-STEM

stem cell therapy

Stem cell treatment for Amyotrophic Lateral Sclerosis

What is ALS?

This disease is named after New York Yankee first baseman Lou Gehrig who developed it in 1939. More formally known as Amyotrophic Lateral Sclerosis (ALS), is a neurodegenerative disease of an unknown cause that is characterized by degeneration of motor neurons in the brain and spinal cord. It often moves very quickly from weakness in limbs to progressive paralysis and eventually, respiratory failure. It typically occurs in the forties through seventies. is caused by a combination of genetic and environmental factors. It has been very difficult to find effective treatments for ALS.

Numerous trials are underway that testing new approaches that use stem cells for ALS treatment

What are Stem cells?

Stem cells are the body’s own cells from which all other cells with specialized functions are generated. These daughter cells either become new stem cells or differentiate into specialized cells (blood cells, brain cells, heart muscle, etc.) There are several sources of stem cells:

  • Embryonic stem cells: come from 3 – 5 days old embryos. These are pluripotent stem cells and can divide into more stem cells or can become any type of cell in the body, and can be used to regenerate or repair diseased tissue and organs.
  • Adult stem cells: found in most adult tissues, such as bone marrow or fat. They have a more limited ability to differentiate into various cells of the body. Lately, it has been found that adult stem cells may be able to create unrelated types of cells, such as bone marrow stem cells forming heart muscle cells.
  • Perinatal stem cells: are found in amniotic fluid and umbilical cord blood.


Stem cell treatment for ALS

There has been a lot of research on using stem cells for the treatments for ALS. Induced pluripotent stem cells (iPSCs) have been used as a source of motor neurons from individual ALS patients to study why and how motor neurons degenerate in ALS. Both upper and lower motor neurons, as well as astrocytes, can be made from iPSCs.

Motor neurons derived from iPSCs can be tracked over time to understand if a test compound has a positive or negative effect. Furthermore, comparing the motor neurons derived from iPSCs can help understand patients’ clinical picture.

More importantly, stem cells can also help in treating the disease. They can be used to produce cells that motor neurons in the brain and spinal cord.


Several trials are underway that testing new approaches that use stem cells for ALS treatment. One of these includes using mesenchymal stem cells can be taken from the patient’s own bone marrow or fat tissue and then modified to enhance their support for dying motor neurons. Another trial is focused on studying the effects of injecting muscle tissue into the fluid surrounding the brain and spinal cord. A recent study in JAMA Neurology reported that the treatment was safe and well-tolerated, resulting in a decreased rate of disease progression during six months after the injections, as compared to six months before treatment.

There is still a lack of high-quality evidence to guide the clinical use of stem cell therapies for the treatment of ALS in the clinic, but the results of recent and current trials have been very encouraging.

Degenerative Arthritis of the Shoulder

Many think that joint pain is just part of the aging process. The old adage that our joints get stiff and we get slower as we age is certainly true, but the pain associated this can be debilitating and have a significant impact on someone’s quality of life. Osteoarthritis, also known as degenerative or wear and tear arthritis is a chronic condition estimated to affect 1 in 10 Americans over the age of 60. Many of these individuals will suffer the condition in their shoulder, making everyday tasks like clearing up or cooking difficult and painful.

What is osteoarthritis? What joints does it affect?


As mentioned previously, osteoarthritis is often referred to as degenerative arthritis or “wear and tear” of your joints. But what exactly does this mean? In a normal joint two bones come together. To stop these bones from rubbing up against one another humans have developed an ingenious cushion layer known as cartilage. Cartilage acts as a sort of shock absorber that stops painful bone on bone contact from occurring. Over time though this cartilaginous layer wears itself down and often doesn’t repair. This results in bone on bone contact and significant pain in the joint affected.


What symptoms are common in osteoarthritis of the shoulder?


There are a number of common symptoms and signs associated with degenerative arthritis of the shoulder. These include:


  • Pain in the joint. This is usually on activity and not at night when you are not moving the joint.
  • A limited range of motion – often the shoulder cannot be moved up high without significant pain
  • An odd looking shoulder is often a key sign. You may be able to see a difference to the other shoulder.
  • People often also report something known as crepitus. This is a creaking that may be audible but is often felt when the joint is moving. It can often feel like something is crunching within the joint.

There are numerous symptoms and signs associated with degenerative arthritis

How is it diagnosed?


The diagnosis of degenerative arthritis is often clinical, but an X-ray can be ordered which will show loss of cartilage amongst other things.


How is it treated?


The treatment of osteoarthritis is an area that is constantly changing and there are many options. Some of the better options include:


  • Non-steroidal anti-inflammatory medications like Ibuprofen or Aspirin. The drugs reduce the production of inflammatory molecules that increased the number of pain signals sent to the brain. However, in some people, they may not be the correct treatment (for instance if you have a history of peptic ulcers etc).
  • Joint injections like steroid injections can be tried to reduce the inflammation in the joint and again reduce the number of pain signals the brain receives.
  • Stem cell therapy is a new treatment offered by specialist clinics across the United States that have been shown to help regrow the cartilage and significantly help the symptoms of shoulder osteoarthritis.

Understanding Arthritis for People Who Experience this Common Condition

As we age we are more and more likely to feel aches, pains, creaks, and squeaks of our joints. Many accept this as part of the aging process, but this seemingly forgets the incredible burden of osteoarthritis (also referred to as wear and tear or degenerative arthritis). In fact, 1 in 10 Americans over the age of 60 years will develop the disease. Of these, a significant amount will be in constant pain and some might not find adequate therapy. So instead of accepting osteoarthritis as an inevitability, is there anything one can do to prevent it?

What is arthritis?

Osteoarthritis is a disease of joints that often occurs in people over the age of 60. It is common in the knees, shoulders hips and hands. For those with the disease in their hands, it can be incredibly irritating as it affects their activities of daily living like cooking and cleaning. The pain and lack of movement are often very frustrating.

By understanding what osteoarthritis is, we can get a better understanding of how to prevent it. When two bones meet at a joint the body uses a protective sheath known as cartilage to stop bone on bone rubbing known as “eburnation”. Over time (or with injury etc) the cartilage can become worn down and result in a bone on bone contact. This results in pain and a reduced range of movement in the affected joints.

What increases your risk of arthritis?

Prevention of arthritis starts with understanding what increases the risk of arthritis and then not doing that thing. Inevitably age plays a huge role but this is not reversible. Other risk factors include:

  • Being over 50 significantly increases your risk.
  • Being female. Whilst the disease is common in both sexes there seem to be more women affected than men.
  • Obesity is strongly associated with knee and hip osteoarthritis. A famous study known as the Framingham study showed that the 20% of woman who is the heaviest have double the likelihood of developing knee osteoarthritis. However, there isn’t an association with osteoarthritis of the hands.
  • Osteoarthritis is more common in the hands of manual workers. People who do jobs that involve constant fine movement have an increased risk (presumably because they experience more wear and tear).

Osteoarthritis is a disease of joints that often occurs in people over the age of 60

Is there anything you can do to prevent it?

At the moment there isn’t much an individual can do, except for not work in manual jobs, that reduces your risk of osteoarthritis. Many of the factors identified above are not changeable. However, there are a number of new and exciting therapies to treat osteoarthritis. One of these is stem cell therapy, whereby individuals own stem cells are injected into the joint allowing the cartilage to regrow in a way that has not been previously possible. If you or somebody you know is suffering from pain in their hands that they think might be the beginning of degenerative arthritis, get in contact with a specialist clinic to talk about stem cell therapy today.

The Things You Need To Know About Stem Cells and Treatments

Stem cells are generally the foundation of every tissue or organ in the body by which these cells have the ability to develop into other cell types in the body. They are used by medical professionals to replace cells and tissues that are damaged or even lost due to diseases and other conditions. And did you know that Stem Cells can differentiate into other types of cells and divide themselves to produce more of the same cells that are needed to be replaced and this where Stem Cell treatments come into view?

Spinal Cord Injuries Stem Cell Treatment

There is a number of sources where stem cells come from:

  • Embryonic Stem Cells – This comes from embryos that are only three to five days old.
  • Adult Stem Cells – Found in most adult tissues like bone marrow or their fat.
  • Perinatal Stem Cells – Coming from the amniotic fluid inside the umbilical cord which has the ability to change into special cells.

Today, Stem Cell Treatments or Stem Cell Therapy is far better than many conventional treatments available which are not very effective. Because of the wonderful and great features of stem cells, treatment is fast, safe, and be almost completed in a couple of days, unlike other treatment for diseases that would take long for results and effectivity to arise. Stem Cell treatments are now done around the world and are a very promising method for curing diseases. And what are the diseases and conditions that can be repaired, regenerated, and be restored by this method?

  • Spinal Cord injuries due to untoward accidents
  • Alzheimer’s disease which is the leading cause of intellectual and social skills
  • Parkinson’s disease and other neurological conditions
  • Diabetes
  • Heart Muscle cells that are damaged by a heart attack

Stem Cell treatment is an amazing technique where many of the injuries that a certain individual has experienced could be repaired without the need of major surgery, giving that person the ability to go back to the things that they normally do every day. Here are other conditions that the Stem Cell therapy can target and heal.

  • Arthritis in joints
  • ALS (Amyotrophic Lateral Sclerosis), which destroys neurons controlling muscles.
  • Ankle sprains which tear tissues from sports or other activities.
  • Tendonitis
  • Achilles tears
  • Autism
  • Autoimmune diseases such as Lupus and Psoriasis
  • Cartilage defects
  • Back pain
  • Fractures
  • Kidney Failure

Stem Cell treatments are now known all over the world and are performed with a high success rate. The need for surgery is lessened thanks to stem cell methods. People are now enjoying lives back to their old selves that were hit by certain diseases and conditions, thanks to the ever-developing treatments that are readily available.


The body’s improvement after the treatment can be felt after 6-8 weeks and some as fast as 3 weeks and will have a continuous improvement over 6 months. The recovery from the stem cell treatment may cause mild soreness from the injection for a week which will dramatically disappear afterward.

Nowadays, we have the technology, the manpower, the knowledge, and equipment to fight diseases and conditions that can impair our well-being which destroys the future. We are just thankful that the ever-evolving technology is here that can change the course of lives of others who suffer physical and mental stress due to conditions of the body. Medicine and science hand in hand creates methods that we never thought would exist today, creating a world more active and colorful.

Do you Have Post-Laminectomy Syndrome? Stem Cells Treatments May Help

Post-Laminectomy Syndrome

If you are experiencing back pain following laminectomy surgery, you must seek medical help to ascertain what may have happened. Of course, it can take time for the body to heal after surgery and so, in these cases, it may just be discomfort as the body is healing. But, some do develop further pain following surgery which may be because the surgery was unnecessary, or, the desired result was not achieved. Most people do not have post laminectomy syndrome but, it is worth asking the question. So that the doctor can give you the best advice, do keep a note of where the pain is experienced. For example, are you experiencing pain in the back still or, do you now have leg pain?


Potential Causes


It may be that small fragments of the disc are still in place and this may be the cause of any irritation.

There may be a build of scar tissue, the nerve root could be compressed or even, disc herniation. Other causes include joint hypermobility or even, facet joint issues. There could even be systemic reasons, and these include autoimmune disorders or even diabetes.


Most commonly, people tend to experience back and leg pain afterward. This can be sufficient enough to limit or restrict you on a day to day basis and is likely to impact sleep patterns too. If the pain is considerable, then it can affect all areas of life and impact on an emotional level too.


Visit your doctor to see whether the tenderness at the site of the surgery is apparent. The doctor will provide an examination and, notice how you are walking and check your posture generally. There may even be increased pain following surgery due to sleep problems, or where there are feelings of anxiousness, depression and, even smoking could even be a trigger. There is certainly a known link between back pain and cigarette smoking.


Axial spinal pain is not uncommon, this may be attributed to abnormalities around the spinal column, perhaps the infection or bleeding through surgical complications. There could also be a neurologic pain, expressed by cold or heat because of injuries to the nerves.


Pain relief


Every person experiences pain differently following this type of surgery and so, pain relief will be treated on an individual level. Pain medication will be prescribed depending on the level of pain, but, you may be prescribed morphine-based medication. Due to the addictive nature of such pain relief, you will be monitored to ensure no dependency on them.



Following observation and diagnosis, you may be prescribed physical therapy as this will help with core strength and movement too. A TENS unit electrical stimulation treatment may be offered, and this works well for pain relief. There are many options for consideration, but your doctor will guide you. Epidural nerve blocks, radiofrequency treatments, and even platelet-rich plasma therapy might be perfect for you. Your doctor will also look at the potential for stem cell therapy as this can be useful if you have Post-Laminectomy Syndrome. Stem cells help to regenerate and boost healing for cells at the damaged site and this means, your back can be restored to good health.

How Exercise Can Help Combat Foot Arthritis?

 Foot Arthritis

Have you been struggling to walk in late? Have you experienced aches and pains in the ankle or foot? If yes, you may have foot arthritis. Osteoarthritis is one type of arthritis caused by wear and tear to the joint. You may find that the joint starts to swell and in time, there may be some deformity. Arthritis is an umbrella term for one hundred or more diseases which affects the joints. Translated, arthritis simply means joint inflammation although, for many people, the word arthritis incites fear as these conditions have the potential to impact life on many levels.


Unfortunately, arthritis can be extremely painful, especially when affecting weight-bearing joints. The bones begin to grate against each other and this leads to the soft tissues of the joints also breaking down. Osteoarthritis is often associated with age. It’s certainly the most common of the arthritic conditions and is a degenerative disease.


Taking control of osteoarthritis.


Although seeking medical advice is paramount, there is much that can be done to keep osteoarthritis at bay. This includes exercising the joints to keep mobility. It is important to be gentle and to only exercise as much as you can without feeling pain. The joint may feel stiff and inflexible but, do this several times a day at least. Any movement is better than none. It is so important to retain as much flexibility as is possible. Yoga as an exercise system can ensure flexibility of the whole body and works well to combat arthritis generally and it will certainly help alleviate the potential for future joint pain.


The following are specific exercises to help offset the potential for foot arthritis and these include:


  • Toe pull – place an elastic band around all the toes and then, working against the resistance of the band, spread your toes wide. Repeat this up to 10 times.
  • Toe curl – If you have small circular objects or, marbles, spend some time trying to pick the marbles up using your toes only.
  • Achilles stretch – Standing up, place your palms flat on the wall and then, lean towards the wall. Place one foot back and one forward. Both heels should be on the floor and this stretches the calf muscles and Achilles tendon. Repeat three times.
  • Ankle alphabet – Sitting in a chair, place both feet flat on the floor. Lift the foot with arthritis from the floor and with your foot extended, try to slowly trace all the letters of the alphabet. Repeat this on the other foot too even if there is no sign of arthritis.


Look after your feet.


When you have osteoarthritis, comfort will suddenly mean everything. You must look for shoes that provide support and that fit properly.


  • Choose rubber soles for extra cushioning
  • Make sure the shoe is flexible
  • Ensure that the fit is correct
  • Avoid slip-on shoes


On a day to day basis, there is much that you can do to stop osteoarthritis from becoming worse. But, it is important to have a medical assessment to ensure that the condition is monitored. Arthritis can be a progressive condition and pain management is important as well as treatment to prevent it from becoming worse. Physical therapy may be useful to work alongside your exercise regime and you can also use arch supports or pads to help support your feet when walking.


There are many different types of medical treatments available and this will be discussed in full when you have your doctor’s appointment. It is worth considering stem cell therapy if offered as it has been providing excellent results for arthritic joints. Degenerative diseases now tend to heal much quicker and stem cell therapy promotes natural healing because it promotes the repair of tissues within the joints, thereby increasing mobility and flexibility.

Coping with Painful Elbow Arthritis

Painful Elbow Arthritis

Elbow arthritis is not as common as arthritis that affects other joints. The hands, hips, and knees tend to suffer more but the disease is still very painful in this area of the body and in some ways, can be more damaging to everyday functions, especially if both elbows are attacked.

Three types of arthritis may affect the elbow.

• Osteoarthritis
• Rheumatoid
• Post-traumatic

Osteoarthritis is relatively uncommon in the elbow joints but can cause much in the way of misery as it tends to make straightening out the joint very painful. Often linked to sports or heavy repetitive labor, it has a simple wear and tears effect on the joint. It would normally only be active in the one elbow that had the most strain.

Rheumatoid arthritis is the main culprit when it comes to elbow arthritis and can be extremely painful. It also can be even worse because it can affect both elbows at the same time, making normal daily activities awkward and painful. There is usually swelling with rheumatoid arthritis and this increases the pressure on the joint. It has a far-reaching effect on daily life.

Post-traumatic arthritis is where some trauma has damaged the elbow in the past and arthritis has set in. A dislocation or a fracture can often lead to torn and damaged cartilage and painful arthritis can develop from that.

Most people tend to cope with elbow arthritis better than when the lower body joints have been attacked, this is because elbows are rarely weight-bearing and most activities do not require the complete range of movement. Carrying a dinner plate from the kitchen to another room can be done with a locked elbow but if walking, the leg joint still needs to bear the full weight. That said, it is important to not detract from the pain and anxiety elbow arthritis can cause.

So, what can be done to help or cure elbow arthritis?

The first port of call in the treatment of any form of arthritis will be medication to ease the swelling and to block some of the pain. You may be experiencing some of the symptoms listed below:
• Locking of the elbow joint
• Swelling around the joint
• A grinding sensation when straightening the elbow out
• An inability to gain the full range of movements

Physical therapy will help to give back some movement and, steroid injections can ease the pain, but relief will not last long. If patients are not responding well to pain medication or treatment, surgery is often the next step. The removal of degenerated cartilage is often carried out, but a complete replacement of the joint is quite often the only option.

Stem cell therapy is now a very effective way of treating all degenerative diseases that affect joints. There are very few side effects with this kind of treatment as the body is basically being used to treat itself. Stem cells are taken from one part of the body and introduced to the damaged area. Stems cells promote healing growth and this treatment has been very successful in treating elbow arthritis.

This treatment is becoming more successful every year and may well be the way forward in the future of dealing with arthritis.

Sciatic Pain Treatment – Signs of Underlying Medical Concerns

Sciatic Pain TreatmentIf you suffer from sciatica, you will know just how intense the pain is. It infiltrates into all areas of life because the movement is restricted and even, sitting down for long periods can be excruciating. Unfortunately, it can take up to 6-weeks for improvement to be noted and medical treatment may be necessary during that time. The sciatic nerve is the largest single nerve in the body and it has various nerve roots that branch out from the spine which combines and make up the sciatic nerve. Pain occurs when compression of the nerve occurs at the point of origin.

Although people tend to think of sciatica as being a stand-alone condition, it is often a symptom of other underlying medical conditions and so, seeking medical advice is paramount.


These other conditions include:

  • Lumber herniated disc – often called ruptured disc, protruding discs or slipped disc. It occurs when the inner material of the disc herniates through the outer layer and this creates a pinching/irritation of the nerve.
  • Lumbar spinal stenosis – this is related to the natural aging process of the spine and commonly affects those over the age of 60. It often coincides with arthritis of the spine which is also a contributing factor for sciatica. There is a narrowing of the spinal canal which may occur through a bulging disc, enlarged facet joints or, soft tissue overgrowth.
  • Degenerative disc disease – again, this occurs with age and is generally diagnosed when inflammatory proteins from within are exposed. These irritate the nerve root.
  • Sacroiliac joint dysfunction – when this joint becomes irritated, it can also aggravate the L5 nerve. This nerve which is located on the top of the sacroiliac joint will cause pain similar to sciatica and certainly, leg pain will occur.
  • Isthmic spondylolisthesis – where a small stress fracture occurs, one vertebrae may slip onto another and the nerve is pinched leading to sciatic pain.

The symptoms of sciatica are intense. Pain radiates down the leg, potentially affecting the foot and the toes. There may be a burning or tingling session or even a sense of numbness. Weakness in the leg may also make it difficult to move. There may be a consistent pain in one buttock and, generally, the pain of sciatica will increase when in a seated position.

Sciatica rarely occurs before the person is 20-years of age and, typically develops when someone is in their 40’s or 50’s. It is a common condition and potentially, affects over 40% of the population. This is an injury that does not just occur but rather develops and this is why medical advice is important to discover any underlying issues.


Additional reasons as to why sciatica occurs include:

  • Muscle strain – where there is inflammation or muscle spasm this can increase pressure to the nerve root.
  • Scar tissue – where scar tissue compresses a lumbar nerve root, the symptoms of sciatica can be experienced
  • Pregnancy – due to weight gain, hormonal changes and changes to the center of gravity, this can also lead to sciatica being experienced.


Sciatica Pain Treatment

In the main, treatment will include rest and applying hot or cold compresses along with anti-inflammatory over-the-counter medications such as ibuprofen. Following a medical diagnosis, anti-seizure medications or muscle relaxants may be prescribed to help alleviate the symptoms. To aid recovery, you may be offered physical therapy which helps to strengthen the muscles of the back and improves posture. Flexibility will also be reviewed. If the pain is incredibly intense, you may be offered steroid injections to help reduce consistent pain but, these do not last for long periods.


Sometimes, surgery is required, and this could be to remove any bone spurs or even parts of any herniated disc so to avoid compression of the sciatic nerve. Surgery will require rest and recuperation over a period thereafter. Stem cell treatments offer much for sciatic nerve recovery and these cells when injected into the relevant place have been shown to heal damage to tissue and it does this by creating new healthy cells. Although typically, sciatic pain treatment can be self-managed, there are options where health concerns require medical assistance.


Wear and Tear – How Osteoarthritis Affects the Hip Joints

Hip joints stiff and creaking? Osteoarthritis is a degenerative disease that can affect anyone, but it is certainly most common in those who are over the age of 45 years, often affecting those joints which are impacted by wear and tear. Millions of people are affected by this condition across the globe and as a ball and socket joint, the hips usually have an excellent range of movement, but osteoarthritis is painful and limiting. It is a serious health condition as osteoarthritis breaks down the rubbery cartilage tissue (made from mainly proteins and water) which covers the ends of the bones. Once cartilage is damaged, the body is unable to make more. The joint itself is surrounded by a fibrous sleeve called the capsule and the capsule lining is called the synovium and it is this that produces the synovial fluid which lubricates and nourishes the actual joint.


Hip joint painThe hips are weight-bearing joints. Degeneration of the joint may cause the person to limp, with pain radiating down the body, often, losing weight may help to take some stress away from the joint but this will not be the cause of the pain. Osteoarthritis in the hip joint is about one third as common as arthritis in the knees. It can be aggravated by over-use even in the home, walking upstairs as a prime example. Stiffness and accompanying pain are the first symptoms but, during advanced stages, deformities to the joint can even result in the legs becoming different lengths.


Pain in the hip joint does not always mean osteoarthritis, it could be inflamed or a strained tendon perhaps, through overdoing exercise. In this case, pain usually dissipates in a day or two. Pain can occur in the groin, in the front of the thigh muscle and even in the knee joint. Sometimes, there is a pain in the buttocks too. If the pain worsens, or, where there has been trauma to the hip by way of a fall, then, medical advice should be sought.


Other hip joint conditions include:

  • Rheumatoid arthritis
  • Psoriatic arthritis
  • Ankylosing spondylitis
  • Paget’s disease
  • Hip fractures

There are many reasons as to why the pain could occur. The joints may not have formed correctly when younger, there could be genetic issues in the cartilage. Pain can manifest in different locations and be either sharp or a dull ache.

Symptoms include:

  • Stiffness when first out of bed
  • Stiffness when sitting for long periods of time
  • Swelling, tenderness or pain in the hip joint
  • Grating feeling or sound in the hip
  • Restricted movement


Correct diagnosis is important. An x-ray is usually taken which may show the narrowing of the joint. A physical examination is likely. In the early stages, painkillers may help – paracetamol or, non-steroidal anti-inflammatory drugs including ibuprofen. Physical therapy can be extremely useful in keeping mobility in the hip, exercises can stretch and strengthen as well as stabilizing. A CT scan or MRI scan may be requested for more in-depth analysis. Steroid injections may help if the hip joint is caused by inflammation and these are often given with anesthetic. Hip replacement surgery was often the outcome and when the hip bone was fractured.

Stem cell treatments can be highly useful for arthritic hip joints and as they are primitive cells already present in the body, they can help to form the necessary cells when added into the painful and damaged area. Once extracted from fat deposits or from bone marrow, they are less likely to be rejected and can even increase regeneration of the joint. Importantly, stem cell treatments are without known side-effects and can also prevent further damage of the hip joint. When hip joints are painful and restricting movement, it is best to seek professional advice.


Join Email List