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MD, PhD, MBA
Dr. David Greene, MD, PhD, MBA, stands at the forefront of regenerative medicine and healthcare innovation, blending clinical expertise with entrepreneurial vision. As the founder and CEO of R3 Stem Cell and US Lead Network, Dr. Greene has dedicated his career to advancing patient care and empowering medical practices through advanced therapies and digital marketing excellence.
A residency and fellowship-trained orthopedic surgeon, Dr. Greene began his journey in medicine with a deep commitment to helping others. After years in clinical practice, he recognized the transformative potential of regenerative therapies and the urgent need for better patient access and education. This insight led him to establish R3 Stem Cell, now a global leader in non-surgical treatment options using stem cell and PRP therapy. Under his leadership, R3 Stem Cell has performed over 26,000 procedures across more than 45 international clinics, offering hope and healing to patients worldwide.
Dr. Greene’s entrepreneurial spirit didn’t stop at clinical innovation. He also founded US Lead Network, a healthcare internet marketing company that leverages artificial intelligence to help medical and dental practices grow their patient base efficiently and ethically. His two books on healthcare internet marketing have become essential reading for providers seeking to navigate the complexities of digital patient acquisition. Recognized as a Top 20 Expert Author by Ezines.com – ranking #15 out of over 470,000 authors and #1 in Pain Management – Dr. Greene’s thought leadership has shaped the way healthcare professionals connect with patients online.
A defining moment in Dr. Greene’s career was his decision to leave clinical practice and focus entirely on innovation and education. “I’ve never been a fan of just settling for the status quo. Innovation is a cornerstone of what makes America great,” he reflects. This philosophy has driven R3 Stem Cell’s mission to provide affordable, high-quality regenerative care and to demystify stem cell therapies through comprehensive training courses and educational content for both providers and patients.
Dr. Greene’s work has garnered international recognition, including a feature on the cover of Corporate Vision magazine, where his commitment to affordable, accessible regenerative therapies was spotlighted. His impact extends beyond business metrics – he is known for his compassionate approach, always prioritizing patient education and ethical practice.
Outside of his professional life, Dr. Greene is inspired by the words of Maya Angelou: “My mission in life is not merely to survive, but to thrive; and to do so with some passion, some compassion, some humor, and some style”. He brings this ethos to his daily work, fostering a culture of innovation, empathy, and continuous learning.
When he’s not leading global healthcare initiatives, Dr. Greene enjoys sharing insights on social media, connecting with colleagues, and pursuing personal interests that keep him grounded and inspired.
Dr. David Greene’s journey is a testament to the power of combining clinical skill, business acumen, and a heartfelt commitment to making a difference – one patient, one practice, and one innovation at a time.
All Posts
What is regenerative medicine? Regenerative medicine refers to the field of medicine that focuses on the replacement or regeneration of human cells, tissues and organs in order to establish normal function. Current modalities such as steroid injections only mask the injury by suppressing inflammatory and
What are amniotic stem cells? Amniotic stem cells are extracted from the amniotic fluid via a process called amniocentesis or after a c-section from a consenting donor. This procedure allows the harvest of stem cells without harming the embryo, although there is a small risk
Amniotic stem cells are considered to be undifferentiated or multipotent cells. They have the ability to differentiate into many lineages of cells. These lineages include skin, bone, blood, muscle, and liver cells. The possibility of using amniotic derived stem cells to heal foot and ankle
Amniotic stem cell therapy for chronic back problems is still in the research phase, but it is showing a lot of promise for patients who suffer from arthritis in the back and spinal area. Since the amniotic derived stem cell are not derived from embryonic
If you have ever had a baby, you probably received unsolicited mail advertising services for banking amniotic stem cells. Since 2009, when the first stem cell bank opened in Medford, MA, cryopreservation and private banking of amniotic fluid stem cells has slowly grown in popularity.
Regenerative medicine is a relatively new and rapidly evolving field in the treatment of pain management, chronic disease, and injuries previously treatable with only surgery. Stem cell therapy has gained the attention of the scientific community over the past few decades, first with investigational research
Human amniotic cells have been used over the past 50 years as a diagnostic tool for prenatal diagnosis of genetic abnormalities in the fetus. Over the past 5 years, however, the potential for using stem cells derived from amniotic fluid has become a reality, especially

Amniotic fluid is the protective liquid that is contained within the amniotic sac of a pregnant mother. Amniotic fluid originates from the mother’s plasma and passes through the fetal membranes by way of osmotic and hydrostatic forces. It is important that the fetus inhales and

In the past few years, we have experienced incredible advancement in the field of regenerative medicine, especially because the use of stem cells has been aggressively explored in order to offer solutions for managing pain and orthopedic conditions. Stem cell therapy has been rapidly embraced