World-Class USA Stem Cell Therapy, Now Available in Istanbul! Get in touch today for a personalized consultation.
World-Class USA Stem Cell Therapy, Now Available in Istanbul! Get in touch today for a personalized consultation.
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Two reasons, and neither is a shortcut on quality.
Regulation differs, and that changes what can be produced: US regulation restricts how far a laboratory may culture and expand mesenchymal cells. In practice that means US clinics generally work with preparations that have not been expanded, so live cell counts are lower and the cost per cell is higher. Turkish regulation permits controlled expansion, which is how we can offer 25 or 50 million live cells at this price.
We would rather state that plainly than imply the price difference comes from somewhere it does not.
Volume: R3 has performed more than 29,000 procedures. That purchasing scale lowers our unit cost, and we pass it through.
For chronic and systemic conditions, live cell count is usually the variable that drives cost, because those protocols call for more cells than a single joint does.
Cell count on a price list is not the same as cells that can do something.
Mesenchymal cells are expanded in culture through successive passages. Their proliferative and differentiation capacity declines as passage number rises, a process described in the literature as replicative senescence. A vial labelled with a high cell count can therefore contain cells that are late passage and less active than the number suggests, and nothing on a price list distinguishes the two.
We release our biologics between passage 2 and passage 4. That limits how many cells we can produce from a given donation, and it is part of why our price is where it is rather than lower.
Four things worth asking any clinic in writing, including us:
If a clinic will not answer those four in writing, that tells you something.
