Stem Cell Therapy for Amyotrophic Lateral Sclerosis (ALS) in Pakistan - Islamabad, Rawalpindi, Karachi, Lahore


Amyotrophic Lateral Sclerosis, also known as Lou Gehrig’s disease or simply ALS, is a term used to describe a number of different neurological diseases. These conditions, which are relatively uncommon, affect the nerve cells which are responsible for controlling physical motions such as chewing and walking.


As the disease progresses, people tend to experience an increase in the severity of symptoms. ALS currently has no cure, but researchers are looking into the use of stem cells for helping to manage ALS.


The Importance of Treatments for ALS


At present, ALS has no treatment. This means that the disease tends to progress, becoming increasingly uncomfortable until the patients die. Patients with ALS generally die within 2-5 years after being diagnosed, continually losing control over their muscles and movements.

This indicates the serious need for treatment for ALS patients. Unfortunately, the underlying cause of the disease is difficult to specify. This makes it challenging for researchers to provide effective treatment.


How Does Stem Cell Therapy Work?


There are a number of different stem cells. These stem cells are employed for various purposes. The most commonly used stem cells include:


  • Endogenous stem cells. These are stem cells that are already present in the human body. They can be found in a variety of tissues including the bone marrow, skin, and brain.
  • Induced pluripotent stem cells (iPSCs). These are stem cells that can be made from skin cells called fibroblasts. By introducing adult skin cells into a solution with various hormones, cells can be triggered to revert into their original state: stem cells. These cells have, so far, proven to be the most useful for managing ALS.
  • Embryonic stem cells. These are cells that are produced during the development of the human embryo. Due to controversy and ethical concerns, the focus of many stem cell researchers has shifted to the use of iPSCs.
  • Mesenchymal stem cells. These cells, often derived from bone marrow, can help improve nerve function and fight inflammation.


Using iPSC Stem Cells for Managing ALS


iPSCs are stem cells that may prove to be useful for managing ALS.

iPSCs are taken from adult tissues – including those of the patients who may be struggling with ALS. These cells have the ability to develop into astrocytes. Astrocytes are cells which can help to support the function of nerve cells.

Research shows the use of mesenchymal cells is viable for managing ALS. These cells are known to help protect the nervous system. They can also help the body produce neurotrophic factors: compounds are known to help support the health of the nervous system.


There is no doubt that these stem cells show promise for helping to improve nerve function. Since ALS is a condition that affects the nervous system, many researchers are excited about the potential of stem cell therapy for managing the problem.

Researchers have also begun to investigate the use of different pluripotent stem cells. These cells can be coerced into adopting certain roles that may be useful for treating ALS.


Stem cell therapy for Amyotrophic Lateral Sclerosis (ALS) is offered by R3 Stem Cell International in Pakistan. Contact us Today at +917947515066 for an Evaluation for stem cell treatment!