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Tag Archive: bone marrow

Read This Before Considering Bone Marrow Stem Cell Therapy

There are ISSUES with Bone Marrow Stem Cell Procedures

It’s important before undergoing a bone marrow stem cell therapy procedure that you truly understand a few facts. First of all, it should be obvious that the procedure involves you being the donor of the bone marrow. The provider will harvest the bone marrow from your pelvis. While the risk of infection is small and there is no risk of rejection, those are not advantages compared with other types of stem cell treatment. For instance, amniotic and umbilical cord tissue don’t cause rejection either, and the risk of infection is minimal.

Bone Marrow Procedures OFTEN Cause Chronic Pain

 

The first consideration with this is that the needle used for the harvest is fairly large and it is going through an extremely sensitive area. The covering of your pelvis has a ton of nerve endings and may hurt significantly with the procedure. In fact, several studies have shown up to a 40% incidence of chronic pain after a bone marrow harvesting. Can you imagine having successful knee pain relief only to trade it for pain in your hip area chronically?

 

The Amount of Stem Cells in Your Bone Marrow is a PROBLEM

 

The biggest concern with using bone marrow for stem cell procedure is simply a matter of numbers. Once a person reaches the age of 50, the amount of stem cells in one’s bone marrow literally drops off a cliff. There is an exponential drop in the number of stem cells and other regenerative cells that are available. At the age of 50, there is a 90% drop in stem cells in one’s bone marrow, and by the age of 70 that drops by 97%!

 

Bone marrow stem cell procedure’s can work very well for those in their 20s and 30s. This would include athletes and those in categories such as post traumatic extremity arthritis. But for those who have degenerative arthritis and are over the age of 50, it is a TERRIBLE idea to consider bone marrow stem cell therapy.

Bone Marrow Stem Cells Get Lazy

 

 

Another interesting fact that has come from research out of Case Western Reserve University in Cleveland, is that stem cells from the bone marrow do not work as well with increasing age. So in addition to their being a quantity problem, there is also a quality issue as well. The stem cells that we make get lazy, and there are also not enough of them as we age.

 

The argument that you should have a bone marrow procedure because it is your own tissue is also not valid. Donated tissue from the amniotic fluid, placenta or umbilical cord does not get rejected in the human body. The reason is that during processing, any DNA factors are removed. This leaves the tissue immunologically privileged. In over 10,000 cases to date, our Centers of Excellence have never had a rejection, disease transmission, or a deep infection.

 

The stem cell and regenerative counts in the tissue are exponentially higher than what is seen with bone marrow or adipose. I will cover adipose in a separate article.
With over 30 R3 Stem Cell Centers of Excellence nationwide, R3 is the nation’s leader in regenerative procedures. Not only does this include arthritis and soft tissue conditions, but also neurodegenerative, auto immune, COPD, kidney failure and much more.

 

Simply call us today at (844) GET-STEM so we can set you up with a free consultation at a center close to you.

The Real Problem with Bone Marrow Stem Cell Therapy

There’s a lot written online these days about stem cell therapy using one’s own bone marrow. Some providers will say “you should only have your own bone marrow used, bone marrow is better for regenerative medicine,” etc. This is concerning as it’s mostly NOT a good idea.

When you really look at using one’s own bone marrow, there are TWO GLARING PROBLEMS that should be taken into consideration. The first issue simply comes

Young athletes are great bone marrow stem cell candidates

down to pure math. When a person is in his or her 20s or 30s, the amount of regenerative cells available is plentiful. For instance, when an athlete is considering undergoing a regenerative procedure, bone marrow may be an excellent option. For an individual in his or her 30’s with a post traumatic cartilage defect, it also makes sense to consider bone marrow procedures.

However, once a person reaches the age of 50, undergoing a bone marrow procedure is mathematically NOT a good idea. Studies have shown that the amount of stem cells available in one’s bone marrow drops exponentially as we age.

Specifically, by the age of 50, that amount drops by about 90%. By the age of 70, it drops by over 95%. In addition, researchers at Case Western have shown the stem cells that are still present do not function as well as those when a person is younger. Basically, stem cells in older individuals get LAZY.

Studies in the past have also shown a significant problem with what is obtained even under the best of circumstances with a bone marrow aspiration. With current techniques, the needle is placed into the iliac crest of the pelvis. Approximately 60 mL of bone marrow is aspirated for use.

What exactly is in that bone marrow?

That question has been answered by studies looking at the composition. The first 2 mL contains a decent amount of stem cells. Unfortunately, the rest of the 60 mL mostly consists of blood. This has very few stem cells and not very many regenerative cells either.

So in addition to age becoming a mathematical liability for the amount of cells we have available, the current techniques for aspiration hurt the situation even more.
The combination of the mathematical decay of the amount of stem cells we have available with aging, the decrease in function of what stem cells remain, and the current technical deficiencies with aspiration all add up to a sub-optimal regenerative procedure using one’s own bone marrow.

Complications with the Aspiration

And if that wasn’t enough to discourage people from undergoing a bone marrow procedure, consider the potential complications of the iliac crest aspiration. On average, studies show a 35% incidence of chronic pain from the aspiration. This means a person may have pain that last well over six months afterwards.

In addition, there have been reports of pelvic fractures, vascular injury, nerve injury and even a bowel perforation can occur. Imagine going in for a simple bone marrow stem cell procedure and ending up needing a blood transfusion and a bowel repair!

For the younger population, bone marrow should still be in the conversation. However, we simply have much better options available today for regenerative procedures. Umbilical cord and amniotic stem cell treatments have been shown in many peer reviewed studies to be safe and very effective for many conditions.

In over 10,000 cases performed over five years, R3’s Centers of Excellence have not experienced any disease transmission, deep infection, no rejection, and of course no chronic pain as no aspiration is necessary.

With umbilical cord tissue and amniotic fluid being obtained ethically and in accordance with FDA regulations, why risk any of the complications and poor cell numbers associated with a bone marrow procedure?

R3 Stem Cell offers effective regenerative procedures at over 30 Centers of Excellence nationwide. We also have a Concierge center in Las Vegas, where patients from around the country and internationally come for first-rate treatments.

Initial consultations, whether in person or over the phone, are offered complimentary along with an imaging review. Call us today at (844) GET-STEM and we will locate a provider close to you!

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