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Stem Cell Therapy for Sacroiliac Joint Pain

The sacroiliac joint represents the area where the sacrum and the iliac bones meet. The sacrum is the base of the spine, and consists of 5 vertebrae fused together. The iliac bones (2 large vertebrae) are located in the pelvic region, over the sacrum. The sacroiliac joint does not experience a lot of movement, but is essential to connect the spine and the pelvis.

Tailbone Pain Treatment

The main causes of sacroiliac joint pain include muscle tightness, pregnancy, osteoarthritis, differences in the length of legs, cartilage damage, joint infections and injury from impact.

Typical symptoms of sacroiliac joint dysfunction are lower back pain, difficulty bending or standing up from seated posture and the alleviation of pain from lying down.

Sacroiliac joint dysfunctions are diagnosed by physical examination, and imaging tests, such as X-ray and computerized tomography (CT).


Self-care measure can alleviate sacroiliac joint pain, and these include rest, heat application to loosen muscle tension, lower back massage and the use of over-the-counter pain medications (e.g. ibuprofen, acetaminophen). Prescription pain relievers and muscle relaxants can also alleviate the symptoms of sacroiliac joint dysfunction. Physical therapy helps to stretch and strengthen the lower back muscles, thereby helping cope with sacroiliac joint pain. Finally, steroid injections at the site may help reduce painful inflammation, leading to short-term relief of symptoms. Intra-articular prolotherapy is, however, known to be superior to steroid injections in relieving sacroiliac joint pain.

Stem Cell Therapy

Around 10 – 25 % of the patients with persistent lower back pain experience sacroiliac joint pain. Therefore, finding an effective treatment option is necessary to provide relief to this patient population. However, as reported in the literature, the effectiveness of intraarticular or periarticular steroid injections, conventional radiofrequency neurotomy and pulsed radiofrequency are poor.

At the R3 Stem Cell Clinics we are excited to share with you the latest therapeutic advances for different musculoskeletal conditions. For the treatment of stubborn sacroiliac joint pain, the answer might bePlatelet-rich plasma (PRP) therapy and Stem cell therapy.

Stem cells are primitive cells that can undergo differentiation to form different types of cells in the body, such as bone, blood, cartilage, tendon, ligaments, etc. These cells are responsible for healinSacroiliac Joint Injectionsg tissue damages by generating new healthy cells. However, with age, the body loses its ability to attract enough stem cells to the site of injury. In this regard, stem cell therapy delivers a high concentration of stem cells to the affected area to promote natural healing.

It is possible to obtain stem cells from the patient’s bone marrow or fat deposits for the purpose of regenerative therapy. Moreover, allogeneic stem cells, such as amniotic derived stem cells, umbilical cord blood cells, can be obtained from FDA-approved tissue banks. These cells are well-tolerated in patients, and the chances of immune rejection are absent. Finally, platelet-rich plasma can be cultivated from the patient’s blood after enriching for platelet cells, which are known to secrete healing factors (e.g. platelet-derived growth factor, vascular endothelial growth factors, transforming growth factor beta-1, epidural growth factor and insulin-like growth factor-1).
Stem Cells for Spinal Disc
Typical cases that may benefit from stem cell therapy or platelet-rich plasma therapy include:

  • Stubborn cases of low back pain that has to rely on non-steroidal anti-inflammatory drugs (NSAIDS), cortisone injections and physical therapy.
  • Cases wherein sacroiliac joint surgery is the only option left to alleviate symptoms.
  • To correct for spinal degeneration due to lumbar fusion surgery, laser spine surgery, spinal decompression, or discectomy.

Stem Cell Therapy at an R3 Stem Cell Clinic may help considerably with SI joint pain. The treatments available include bone marrow derived stem cell treatments, amniotic stem cell therapy, PRP therapy and fat derived as well.

Call (844) GET-STEM to find an R3 Stem Cell Center near you today!



  1. Hansen H, Manchikanti L, Simopoulos TT, et al. A systematic evaluation of the therapeutic effectiveness of sacroiliac joint interventions. Pain Physician. 2012 May;15(3):E247-78.
  2. Woods AC, Mant MJ. Amelioration of severe psoriasis with psoriatic arthritis for 20 years after allogeneic haematopoietic stem cell transplantation. Ann Rheum Dis. 2006;65(5):697..

Amniotic and Umbilical Cord Stem Cell Treatments

The most revolutionary regenerative medicine treatments now being offered include amniotic and umbilical stem cell treatments. These are FDA regulated and contain growth factors, hyaluronic acid, cytokines and stem cells.

Stem Cell Therapy Offers
Nonoperative Options

With a third of the US suffering from chronic pain, and over a milion each year
undergoing joint replacements in the US, stem cell therapy has a large target audience.
Whether you have a stem cell procedure to get back into sports, avoid hip or knee
replacement or avoid back surgery, regenerative medicine can help!

Contact Us Now!

Corporate Address: R3 Stem Cell
R3 Stem Cell, LLC
32531 N Scottsdale
Ste 105-559
Scottsdale AZ 85266

Phone: (844) GET-STEM
Fax: (888) 892-1831

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