Call US NOW (844) GET-STEM

Call US NOW (844) GET-STEM


Stem Cell Therapy for Degenerative Disc Disease Back Pain

Stem cell therapy for degenerative disc disease is available and works according to recent research studies. In this video, R3 Stem Cell CEO David Greene MD explains the current research results. If you or a loved one is experiencing chronic back pain due to degenerative disc disease, call R3 Stem Cell today!

Stem Cell Therapy for Avascular Necrosis

Avascular necrosis of the hip or knee often leads to chronic, debilitating pain. To date there have not been enough nonoperative treatment options that provide effective relief. Stem cell therapy is proving to be a viable option. In this video, R3 Stem Cell CEO David Greene MD goes through the research on the topic. Call us for treatment today!

 

Stem Cell Therapy for Wound Healing

Nonhealing wounds due to venous leg ulcers or diabetic neuropathy can lead to systemic infection or osteomyelitis, which can result in the need for amputation. Fortunately, treatment with amniotic membrane has been shown to work significantly better than traditional treatments. While the membrane itself has no stem cells in it, there are significant amounts of growth factors. A lot of wound physicians will inject amniotic fluid around the sides of the wound as well to assist with wound closure too!

 

FAQs on Stem Cell Procedures for Elbow Tendonitis

Stem cell procedures are an excellent method to treat elbow tendonitis thanks to the natural repair and regeneration. Be it tennis elbow or golfer’s elbow, tendonitis is traced to chronic inflammation of an elbow tendon. Stem cell therapy can relieve pain in the short term and restore the damaged tendon in the long term.

What are stem cells?

Stem cells differ from all other cells in our body due to their ability to become most other cells. These cells replicate into cells found in the part of the elbow painbody where these are injected.

What is the source of stem cells used to treat elbow tendonitis?

Stem cells are sourced from the bone marrow, fat cells, or from amniotic fluid.

Fat and bone marrow are harvested from the patient him or herself. Amniotic fluid is harvested from a consenting mother after a scheduled c-section.

How does stem cell therapy treat elbow tendonitis?

Elbow tendonitis encompasses two types of injuries – tennis elbow (lateral epicondylitis) and golfer’s elbow (medial epicondylitis) – both have their origin in tendinitis or degeneration of musculature leading to chronic inflammation of elbow tendons. Tennis elbow occurs in the outer tendons, while golfer’s elbow affects the inner tendons.

Stem cells injected into the area of the injured tendon help to repair and regenerate the damage by converting into tendon cells, while also promoting new blood vessel formation.

How successful is stem cell therapy to treat elbow tendonitis?

Stem cell procedures for elbow tendonitis are popular with both golfers and tennis players.

  • A study carried out by the Jefferson-based Rothman Institute showed 61% of those treated with stem cell therapy for tennis elbow had significant improvement in pain and tenderness compared to 50% in the non-stem cell group over a period of 24 weeks.
  • A study attributed to researchers from South Florida attests the fact that stem cell procedures for elbow tendonitis brings down pain considerably and improves disability.
  • A Stanford University study published in 2006 claims 93% improvement in chronic elbow tendonitis when stem cell procedures are used.
  • A 2012 study reported 66% percent more pain relief from stem cell therapy compared to corticosteroid injections.

What are the advantages of stem cell therapy for elbow tendonitis compared to other treatments?tennis elbow

  • Healing by the human body itself
  • Non-invasive and no need for surgery
  • Complete and fast recovery
  • Outpatient procedure
  • Nonsteroidal

How are stem cells to treat elbow tendonitis harvested?

Stem cells used to treat elbow tendonitis are harvested from the bone marrow or one’s fat (adipose). The procedure takes about half an hour.

Amniotic fluid is obtained from consenting  mothers after a scheduled c-section. The fluid is then processed at an FDA regulated lab and cryogenically frozen until it’s time for the procedure. There are no rejection issues as the fluid is immunologically privileged.

How is the stem cell therapy for elbow tendonitis performed?

The skin above the tendon causing pain is numbed and stem cells are injected into the area. Often times, the needle is also used to “poke holes” in the bone too so bleeding is stimulated for repair. These stem cells start to multiply themselves soon after being injected. These new cells replace the old and damaged cells and anchor the repair job. The process goes on for months.maxresdefault

What are post-procedure cautions to be followed?

You may have to use an elbow sling for a day. Activity should be limited for approximately 48 hours, then resumed as tolerated.

What are the side effects of stem cell procedures for elbow tendonitis?

Complications are unusual and may include infection, bleeding or soreness.

Do I need more than one stem cell procedures for elbow tendonitis?

Patients usually need one stem cell procedure to treat elbow tendonitis. However, at times a second procedure may be necessary for optimal relief.

 

References

Singh A, Gangwar DS, Singh S. Bone marrow injection: A novel treatment for tennis elbow. Journal of Natural Science, Biology, and Medicine. 2014;5(2):389-391.

Lui PPY. Stem cell technology for tendon regeneration: current status, challenges, and future research directions. Stem Cells and Cloning : Advances and Applications. 2015;8:163-174.

Carvalho A de M, Badial PR, Álvarez LEC, et al. Equine tendonitis therapy using mesenchymal stem cells and platelet concentrates: a randomized controlled trial. Stem Cell Research & Therapy. 2013;4(4):85.

Ho JO, Sawadkar P, Mudera V. A review on the use of cell therapy in the treatment of tendon disease and injuries. Journal of Tissue Engineering. 2014;5:2041731414549678.

Young M. Stem Cell Applications in Tendon Disorders: A Clinical Perspective. Stem Cells International. 2012;2012:637836.

Top 5 Definitions in Amniotic Stem Cell Treatments

Stem Cell Injections, Growth Factors, Cytokines, Hyaluronic Acid – WHAT ARE THESE?

When looking at receiving amniotic stem cell treatment to avoid surgery for arthritis, tendonitis, sports injuries, or for wound care or cosmetic purposes, it helps to know what these terms mean. You don’t need to be a PhD, but at least having a basic understanding of the components of the treatment being received can’t hurt! In this video, R3 Stem Cell CEO David Greene explains what they mean.

When you’re ready for treatment, call us at (844) GET-STEM!

 

Top 8 Things to Know About Amniotic Stem Cell Therapy

Amniotic stem cell therapy is now mainstream, and because it’s fairly new people have lots of questions about the treatment. The therapy is extremely low risk, and contains several “ingredients” that are beneficial for repair and regeneration of tendons, ligaments, cartilage and other tissues. While a lot of products on the market have no live stem cells after processing, there are some that do. Hear R3 Stem Cell describe the top 8 things to know about amniotic stem cell treatment.

 

 

Why Is There Great Interest in Stem Cells?

Stem cells, which may be thought of as the body’s natural repair kit, have created a lot of interest amongst medical researchers and doctors. In practical application and experimental trials, these cells have been found to have great power and potential in treating a long list of health care issues, including stem-cellsinjuries to the musculoskeletal system, wound healing, neurological disorders and injuries, heart problems, cancer, and much more.

Practitioners are currently using stem cells to treat various health concerns such as rheumatoid arthritis; ligament, tendon, and bone damage; and wounds. It’s expected that in a few years that list will expand greatly. Needless to say, there is great interest in these amazing powerful and versatile cells. What are the various benefits that can be associated with stem cells? They are numerous.

Greater Understanding of Disease

It’s hoped that researchers and doctors in the lab can learn more about diseases, including how and why they happen, by observing stem cells as they mature to become muscles, nerves, bones, and other tissues and organs. Because stem cells contain the basic components needed to repair the body in that they are the healthy cells that replace those that are damaged or diseased, there’s great hope that we can gain new and important insights into diseases and injuries that will lead to breakthroughs in medicine.

Development of More effective Treatments

In understanding more about disease and injuries and how these cells work in repairing the body, scientists see a future where a wide range of health issues can be addressed with the use of new stem cell therapies. Healthcare challenges that may benefit from this new knowledge and developing therapies include those related to spinal cord injuries, heart disease, stroke, burns, type 1 diabetes, Parkinson’s disease, Alzheimer’s disease, cancer, and osteoarthritis.

Revolution in Transplant and Regenerative Medicine

There’s great interest in stem cells due to the promise they hold for the development of transplant and regenerative medicine. Because of their vast potential to be grown and cultivated into new tissue, stem cells may have applications of which we are not even aware. The entire manner in which we treat very serious conditions and diseases may change drastically and success rates could rise dramatically as stem cell therapies are developed.

R3 Stem Cell is at the forefront of offering regenerative medicine for all types of musculoskeletal conditions. Call us today!

What Are the Latest Research Finding About Stem Cell Therapy Benefits For Knee Arthritis?

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Stem cell therapy has emerged as the most promising treatment to stop and reverse the effects of degenerative disorders, such as knee arthritis. Research publications worldwide attest its effectiveness in fast becoming a non-invasive substitute to surgical method and an alternative source of knee cartilage cell regeneration.

Scientific studies show that stem cell therapy has higher success rate in improving pain and disability associated with knee arthritis compared to any other treatment. The bio-restorative procedure with its unique natural healing ability also stimulates the regeneration of the damaged knee cartilage reversing the effects of arthritis.

How does stem cell therapy treat knee arthritis?

Knee arthritis causes permanent damage to the articular cartilage. As a result, bones in the knee joint rub with each other as we walk or bend the knee. This leads to pain and disability.

Stem cells have the unique ability to self-renew themselves and replicate other cells. When these cells are harvested and injected into the knee affected by arthritis, it triggers redevelopment of the damaged cartilage. Stem cells increase in numbers by self-renewing and differentiating themselves into cartilage cells. These new cells gradually replace the damaged and dead cells and heal the injury. This allows redevelopment of the cartilage and reversal of the damage caused by knee arthritis.

Is stem cell therapy for knee arthritis an alternative to surgery?

Stem cell therapy is fast emerging an alternative to surgical treatment of knee arthritis. Non-invasive, it assures better and permanent healing, pain management, greater freedom from disability, and faster recovery. The procedure completely reverses the damage to the cartilage by helping it to regenerate and thus heals the degeneration associated with knee arthritis.

As stem cells are harvested from the body of the patient, these do not pose any risk of rejection. Once the healing is complete, you regain knee strength equal to the pre-arthritis level and lead a pain-free life for a significantly longer period. The degree and duration of relief is far superior to the outcome of any other treatment or pain management method.

What Does The Latest Research Show?

The latest research on stem cell therapy highlights its wider application to treat and reverse the damage caused by degenerative disorders. According to research findings published in the Expert Opinion in Biological Therapies, stem cells are able to renew the damaged knee cartilage and undo the effects of arthritis. In a wider study reported in the Clinical Journal of Sports Medicine, researchers discovered that almost a third of patients studied had their cartilage degradation completely reversed within 12 months of having the procedure.

The results of a pilot study published in 2013 termed stem cell therapy a breakthrough treatment for patients suffering from knee arthritis. It provides significant improvement relieving pain and disability without any hospitalization or invasive surgery. The Stem Cells journal claims accelerated healing and recovery from knee arthritis is possible when a patient is treated with stem cell therapy.

The outcome of an 18-patient study published in the Stem Cells Translational Medicine journal that asserts that “a single injection of stem cells reduces pain and inflammation” and “improves mobility.” All were French and German patients aged 50 to 75 and had debilitating arthritis symptoms in their knees, such as severe inflammation, considerable pain, and crippling disability, for more than 12 months. Divided in to three groups – low-dose, medium-dose, and high-dose stem – each had a single injection of stem cells. A review after six months revealed that all patients had improvements as far as the severity of pain, functional disability, and mobility are concerned. Researchers observed “statistically significant” recovery even in the group with the lowest dose.

An analysis of current research on pharmacologic and regenerative therapies for osteoarthritis published in the Bone Research journal (Mar, 2016) acknowledges stem cell procedure as a “long-term solution to repair and regenerate cartilage, alleviate symptoms and finally delay progression of osteoarthritis.”

Meanwhile scientists at the Whitaker Biomedical Engineering Institute in Johns Hopkins have successfully generated precursor cartilage cells from stem cells. Sponsored by the Arthritis Foundation, the project showcases the promise of creating new bone or cartilage that could replace or repair the damage to the knee caused by osteoarthritis.

Encouraged by the “bio-restorative” qualities of stem cell therapy, the Rush University Medical Center ran the first ever nationwide clinical study of Cartistem – a first of its kind cartilage regeneration stem cell drug – between 2013 and 2015. Injected in to the knee area, it is touted to repair knee cartilage damaged by osteoarthritis. The trial that ended in May 2015 was promising and a detailed outcome report is expected next year.

Researchers at the St. Louis-based Washington University School of Medicine have also developed a new stem cell technique that can resurface an arthritic knee joint. As reported in the Proceedings of the National Academy of Sciences journal, stem cells are programmed to develop a new cartilage that has anti-inflammatory molecules, which prevents reoccurrence of arthritis.

Mesoblast, a leader in stem cell medicines, made a presentation at 2016 Amsterdam World Congress of the Osteoarthritis Research Society International about its MPC-75-IA drug made to turn around effects of knee arthritis. The manufacturer claimed that a single shot of its product, an intra-articular stem cell injection, was capable of significantly improving “pain, disability, cartilage thickness, and joint structure within 24 months.”

R3 Stem Cell offers stem cell therapy for knee arthritis at clinics nationwide. Treatment is offered with amniotic stem cell therapy for knees, bone marrow and adipose derived stem cells. Call (844) GET-STEM today!

References

Yves-Marie Persa, Lars Rackwitzc, Rosanna Ferreiraa, et al. Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial. STEM CELLS Translational Medicine; May 23, 2016, sctm.2015-0245

Wei Zhang, Hongwei Ouyang, Crispin R Dass. Current research on pharmacologic and regenerative therapies for osteoarthritis. Bone Research 4, Article number: 15040; 01 March 2016

Franklin Moutosa, Katherine Glass, Sarah Compton. Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing. Proceedings of the National Academy of Sciences; August 2, 2016; vol. 113 no. 31

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