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Call US NOW (844) GET-STEM


Author Archive: David Greene

The Real Problem with Bone Marrow Stem Cell Therapy

There’s a lot written online these days about stem cell therapy using one’s own bone marrow. Some providers will say “you should only have your own bone marrow used, bone marrow is better for regenerative medicine,” etc. This is concerning as it’s mostly NOT a good idea.

When you really look at using one’s own bone marrow, there are TWO GLARING PROBLEMS that should be taken into consideration. The first issue simply comes

Young athletes are great bone marrow stem cell candidates

down to pure math. When a person is in his or her 20s or 30s, the amount of regenerative cells available is plentiful. For instance, when an athlete is considering undergoing a regenerative procedure, bone marrow may be an excellent option. For an individual in his or her 30’s with a post traumatic cartilage defect, it also makes sense to consider bone marrow procedures.

However, once a person reaches the age of 50, undergoing a bone marrow procedure is mathematically NOT a good idea. Studies have shown that the amount of stem cells available in one’s bone marrow drops exponentially as we age.

Specifically, by the age of 50, that amount drops by about 90%. By the age of 70, it drops by over 95%. In addition, researchers at Case Western have shown the stem cells that are still present do not function as well as those when a person is younger. Basically, stem cells in older individuals get LAZY.

Studies in the past have also shown a significant problem with what is obtained even under the best of circumstances with a bone marrow aspiration. With current techniques, the needle is placed into the iliac crest of the pelvis. Approximately 60 mL of bone marrow is aspirated for use.

What exactly is in that bone marrow?

That question has been answered by studies looking at the composition. The first 2 mL contains a decent amount of stem cells. Unfortunately, the rest of the 60 mL mostly consists of blood. This has very few stem cells and not very many regenerative cells either.

So in addition to age becoming a mathematical liability for the amount of cells we have available, the current techniques for aspiration hurt the situation even more.
The combination of the mathematical decay of the amount of stem cells we have available with aging, the decrease in function of what stem cells remain, and the current technical deficiencies with aspiration all add up to a sub-optimal regenerative procedure using one’s own bone marrow.

Complications with the Aspiration

And if that wasn’t enough to discourage people from undergoing a bone marrow procedure, consider the potential complications of the iliac crest aspiration. On average, studies show a 35% incidence of chronic pain from the aspiration. This means a person may have pain that last well over six months afterwards.

In addition, there have been reports of pelvic fractures, vascular injury, nerve injury and even a bowel perforation can occur. Imagine going in for a simple bone marrow stem cell procedure and ending up needing a blood transfusion and a bowel repair!

For the younger population, bone marrow should still be in the conversation. However, we simply have much better options available today for regenerative procedures. Umbilical cord and amniotic stem cell treatments have been shown in many peer reviewed studies to be safe and very effective for many conditions.

In over 10,000 cases performed over five years, R3’s Centers of Excellence have not experienced any disease transmission, deep infection, no rejection, and of course no chronic pain as no aspiration is necessary.

With umbilical cord tissue and amniotic fluid being obtained ethically and in accordance with FDA regulations, why risk any of the complications and poor cell numbers associated with a bone marrow procedure?

R3 Stem Cell offers effective regenerative procedures at over 30 Centers of Excellence nationwide. We also have a Concierge center in Las Vegas, where patients from around the country and internationally come for first-rate treatments.

Initial consultations, whether in person or over the phone, are offered complimentary along with an imaging review. Call us today at (844) GET-STEM and we will locate a provider close to you!

Does Stem Cell Therapy Work with Bone on Bone Arthritis?

One of the main questions we receive from individuals considering regenerative therapy for an arthritic joint is “Will the stem cell therapy work if I have bone on bone arthritis?” Interstingly, the answer is yes!

We didn’t always think it would help. When R3 first started over five years ago, we told providers it probably wouldn’t work. Thankfully, we were wrong! The outcomes proved to be exceptional over 80% of the time.

As the past five years have gone by and patient after patient has gotten dramatically better from the treatment, we have learned what is most likely happening with the joint treatment.

How Arthritis Occurs

 

Throughout life, people make cartilage at the same rate. It doesn’t matter whether a person is twenty or eighty, cartilage formation occurs consistently. The issue concerns the rate of cartilage loss. Unfortunately, with age comes an increased rate of cartilage loss. So the ratio of formation to loss turns into a mismatch.

This leads to an overall loss and degenerative arthritis. What’s being accomplished with a regenerative procedure (e.g. umbilical cord stem cell therapy), is putting the ratio back into the patient’s favor. It is NOT a cure or a complete fix, anyone who says that is not being realistic.

With the ratio being put back into the patient’s favor, cartilage formation can accumulate in a joint. Often times, noticeable joint improvement will occur on x-rays over time. It does not need to be a ton, simply a couple millimeters will usually be enough to create tremendous relief for patients.

How long will the relief last from a regenerative injection?

 

This is variable, and there is no set time frame. We have seen patients treated five years ago doing fantastic, while others may need a repeat treatment after a couple years. A person may not need another stem cell treatment, but may just benefit from a PRP treatment. The relief usually starts within the first month, and continues to improve for over six months.

There is no age limit to the treatment. R3’s Centers have seen patients upwards of age 102. The desire may simply be to walk farther, play more with the grandkids or play golf more often. Thankfully, the treatments are extremely safe in addition to being effective over 80% of the time.

How is Amniotic and Umbilical Cord Tissue Regulated?

 

Amniotic and umbilical cord tissue is strictly FDA regulated. During processing, any DNA factors are removed so it does not lead to rejection. The best labs, such as the ones R3 works with, ensure very high cell viability by not using radiation and only minimal preservative. This is one reason the outcomes at our Centers has been so amazing.

With the outcomes being so exceptional, over 95% of patients considering treatment at R3 now ask for amniotic and umbilical cord tissue treatment. Along with the outcomes, there is no need for harvesting so the potential for chronic donor site pain is avoided. When a bone marrow or adipose procedure is undergone, the potential for chronic donor site pain is over 30%, and with each year that goes by the regenerative cell counts in the human body decreases considerably.

 

R3 Stem Cell has over thirty Centers of Excellence nationwide. All of them offer a free consultation, and the providers are first rate. Call today to set up your visit to R3, where Regenerative Medicine is Made Easy!

R3 Stem Cell Founder Appears on Longstanding Radio Show Stepping In

For over 20 years, Nurse Jackie Tucker has been the host of Stepping In on KSCO in Santa Cruz CA. She discusses current healthcare topics with respected members of the healthcare community nationwide.

When R3 Stem Cell Founder and CEO David Greene, MD, MBA was asked to participate with Jackie on a recent show, he immediately said yes. “This is information people really want to hear, and Jackie’s got a great audience. She’s very professional and her reputation is stellar, so it took me about a nanosecond to say yes!”

Jackie asked questions about PRP and stem cell therapy, including applicability to several conditions. Amniotic stem cell therapy was discussed, along with opportunities for stem cell therapy to treat arthritis, tendonitis, burns, COPD, kidney failure and Alzheimer’s. The show lasted almost an hour.

To hear the entire show, simply click below!

Stem Cell and PRP Therapy for Heel Pain from Plantar Fasciitis

Heel pain from plantar fasciitis affects millions of Americans. Current, traditional treatment options include NSAIDS, night splints, cortisone injections, stretching and orthotics. All too often the heel pain becomes chronic and patients end up deciding on potentially risky surgery. Even if no complications occur, the outcome is pretty much a roll of the dice.

But all is not lost. Research is now showing that PRP and Amniotic stem cell therapy works very well for chronic heel pain from plantar fasciitis. In this video, R3 Stem Cell CEO explains the evidence available. Call us today for top treatment at (844) GET-STEM!

 

Amniotic Stem Cell Therapy is for Real

I realize there are plenty of critics who write negatively about amniotic fluid treatment in regenerative medicine. Rather than writing a LONG blog post about why amniotic stem cell therapy is for real, here are some bullet points. Please watch the video below and you will understand why the treatment is the real deal.

  1. When processed properly, amniotic fluid DOES have viable stem cells. There are plenty of companies that radiate their product during processing, but the FDA does not require that. The video explains this nicely.
  2. You have to keep in mind those who consistently speak negatively about amniotic are promoting a competing product. So when you put it in perspective you can understand why they would want to find something negative. Amniotic stem cell treatment does not require harvesting, the treatment is fast, results have been fantastic and no rejection occurs.
  3. Naysayers harp on the fact that amniotic fluid is not FDA approved. The funny thing is it cannot be FDA approved because it is regulated as a biologic. It cannot be FDA denied either.

The bottom line is amniotic fluid in regenerative medicine has shown amazing outcomes. Another thing you will notice is you don’t need sedation for a harvesting, and the treatments are less expensive predominantly as a result. Watch the video below, then call (844) GET-STEM for treatment!

 

Stem Cell Therapy for Shoulder Conditions

While there is not a ton of research on stem cell therapy for shoulder pain, some studies have been published. This includes stem cell therapy for rotator cuff tears, tendonitis, SLAP lesion, shoulder arthritis, cartilage defects and more. In this video, R3 Stem Cell CEO Dr. David Greene explains outcomes that have been shown in the research. If you or a loved one needs stem cell therapy for shoulder pain conditions, call (844) GET-STEM today!

 

Stem Cell Therapy for Degenerative Disc Disease Back Pain

Stem cell therapy for degenerative disc disease is available and works according to recent research studies. In this video, R3 Stem Cell CEO David Greene MD explains the current research results. If you or a loved one is experiencing chronic back pain due to degenerative disc disease, call R3 Stem Cell today!

Stem Cell Therapy for Avascular Necrosis

Avascular necrosis of the hip or knee often leads to chronic, debilitating pain. To date there have not been enough nonoperative treatment options that provide effective relief. Stem cell therapy is proving to be a viable option. In this video, R3 Stem Cell CEO David Greene MD goes through the research on the topic. Call us for treatment today!

 

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